[The effect of tiofedrine on brain perfusion in patients with cerebrovascular insufficiency].

The influence of intravenous tinofedrine (0.12 to 0.17 mg/kg body-weight) on cerebral blood flow has been investigated in 23 patients (mean age 65 years) with subacute cerebral infarction. The mean cerebral blood flow increased significantly by 20% in the infarcted hemisphere during a treatment period of 12 days. Clinically an improvement of an initially depressed vigilance level was established which was quantified psychopathometrically in 4 patients.