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足月未成熟分娩情况下宫颈用前列腺素凝胶预处理(作者译)

[Priming of cervix with prostaglandin gel during immature birth situation at term (author's transl)].

作者信息

Heinzl S, Ramzin M S, Schneider M, Luescher K P

出版信息

Z Geburtshilfe Perinatol. 1980 Dec;184(6):395-400.

PMID:7222869
Abstract

The article reports on a controlled, randomized double-blind study by which the effect of intracervically applied Prostaglandin in F2 alpha Gel was examined with regard to the cervix during immature vaginal situation. 124 patients were included in the study. 4 of these had to be dropped because of documentation errors. Age, duration of pregnancy and percentage share of primiparae were approximately equal in both groups. The results show that administration of Prostaglandin Gel via the intracervical route can provoke birth within the next 36 hours in more than 75% of the cases. Only 12.8% of the cases belonged to this category in the control group. Results are somewhat poorer in primiparae. Coarser side effects did not occur in our group, and there is also no higher incidence of surgical deliveries. No negative influence on newborn is to be expected. Results are presented, discussed and compared with those communicated in the available literature.

摘要

本文报道了一项对照、随机双盲研究,该研究在未成熟阴道状态下,就宫颈方面对宫颈内应用前列腺素F2α凝胶的效果进行了检查。124名患者纳入该研究。其中4名因记录错误不得不退出。两组在年龄、妊娠时长和初产妇比例方面大致相同。结果显示,通过宫颈内途径给予前列腺素凝胶,超过75%的病例可在接下来36小时内引发分娩。对照组中仅12.8%的病例属于此类。初产妇的结果稍差。我们组未出现更严重的副作用,手术分娩发生率也未更高。预计对新生儿无负面影响。文中呈现并讨论了结果,并与现有文献中报道的结果进行了比较。

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