[DU-total oestrogens, S-unconjugated oestriol and S-total oestriol in hypotrophy. A comparison of the clinical relevance on a quantitative basis (author's transl)].

In 34 risk pregnancies with 34 hypotrophic newborns we determined during the second half of pregnancy the 24-hour urinary total oestrogens, unconjugated oestriol and total oestriol in the serum. By means of graphical evaluation of the pathological ranges in relation to the normal ranges (degree of overlapping) we investigated the relative clinical relevance. In respect of hypotrophy the ratio of dU-total oestrogens: S-unconjugated oestriol: S-total oestriol = 14:2:1. The considerable superiority of diagnosis based on urine in transverse assessment results in a statistically significant time gain of 4 weeks compared with the two serum parameters.