Quante F, Laschner W, Anadere I
Z Orthop Ihre Grenzgeb. 1980 Dec;118(6):968-74. doi: 10.1055/s-2008-1053356.
The article explains the fundamental problems in therapeutic studies of the primary and secondary processes in arthrosis. Many drugs are on the market for treating the secondary phenomena; however, such phenomena can often be assessed only on the basis of "soft" action criteria (verbal information given by the patients). Biochemical examinations of the synovial fluid and methods to assess joint morphology, are particularly suitable for evaluating the primary changes taking place in the joint cartilage. An assessment of the "joint noises" is known in literature as a non-invasive method. An improved method of recording and evaluating these joint noises is suggested. It is characterized by the following features: - registration of signals with defined joint load - classification of the noise phenomena with reference to the joint position, i.e. to joint areas - by separation of the signal into movement cycles elimination of artificial noise producers - evaluation of those signal periods only which are disease-specific. The article shows examples by quoting signals with the respective frequencies for healthy and diseased persons, and explains the suitability of the method in therapy control by describing two examples of surgical treatment.
本文阐述了关节病原发性和继发性病程治疗研究中的基本问题。市场上有许多药物用于治疗继发性症状；然而，此类症状往往只能根据“软性”作用标准（患者提供的口头信息）进行评估。滑膜液的生化检查以及评估关节形态的方法，对于评估关节软骨发生的原发性变化尤为适用。文献中已知评估“关节弹响”是一种非侵入性方法。本文提出了一种改进的记录和评估这些关节弹响的方法。其特点如下：——在确定的关节负荷下记录信号——根据关节位置，即关节区域，对弹响现象进行分类——通过将信号分离为运动周期，消除人为噪声源——仅评估那些具有疾病特异性的信号周期。本文通过引用健康人和患病者各自频率的信号示例，并通过描述两个手术治疗的例子来解释该方法在治疗控制中的适用性。
