Rainer F, Ribitsch V, Ulreich A
Acta Med Austriaca. 1980;7(3):92-5.
The viscosity of "normal" post mortem synovial fluid, and synovial fluid samples of knee joints affected by various joint diseases (inflammatory and non inflammatory) was investigated and compared with flow curves of Hyaluronic acid and Polyacrylamide solutions. The viscoelastic behaviours of synovial fluid seems to be of great importance for the lubrication mechanism of the joints. Differing results of the viscoelastic properties could be determined in different joint diseases. As a result of these changes the lubrication mechanism is impaired and this leads to cartilage wear. Solutions of Polyacrylamide and Hyaluronic acid have been investigated as model-substances, the former showing rheological properties similar to normal synovial fluid. Their application as an artificial lubricant has been investigated.
对“正常”尸检滑液以及受各种关节疾病(炎性和非炎性)影响的膝关节滑液样本的粘度进行了研究,并与透明质酸和聚丙烯酰胺溶液的流动曲线进行了比较。滑液的粘弹性行为似乎对关节的润滑机制极为重要。在不同的关节疾病中可以确定粘弹性特性的不同结果。这些变化导致润滑机制受损,进而导致软骨磨损。已对聚丙烯酰胺和透明质酸溶液作为模型物质进行了研究,前者显示出与正常滑液相似的流变特性。还研究了它们作为人工润滑剂的应用。