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[生物流变学对风湿性关节疾病问题的贡献]

[Biorheological contribution to the problem of rheumatic joint diseases].

作者信息

Ribitsch V, Rainer F, Ribitsch G, Schurz J, Klein G

出版信息

Z Rheumatol. 1981 Sep-Oct;40(5):199-204.

PMID:7314964
Abstract

The rheological properties of synovial fluids from patients with different rheumatic diseases are discussed. Viscosities of 73 samples were determined and are compared to a standard of "healthy" human synovial fluid p. m. and to bovine synovia. Typical differences between "healthy", degenerative and inflammatory synovial fluids could be discerned. These differences can be characterized with several rheological parameters. The mechanism of lubrication in joints and the role of synovial fluid as a lubricant are discussed. Rheological properties of polymere solutions which could serve as a substitute for sick synovial fluids are described and compared to the properties of healthy synovia. Several possibilities for molecular changes which could account for the deterioration of synovial fluids in patients with different rheumatic diseases are discussed.

摘要

本文讨论了不同风湿性疾病患者滑液的流变学特性。测定了73份样本的粘度,并与“健康”人午后滑液标准以及牛滑液进行了比较。可以辨别出“健康”、退行性和炎性滑液之间的典型差异。这些差异可用几个流变学参数来表征。文中讨论了关节润滑的机制以及滑液作为润滑剂的作用。描述了可用作病态滑液替代品的聚合物溶液的流变学特性,并与健康滑液的特性进行了比较。讨论了几种可能导致不同风湿性疾病患者滑液恶化的分子变化情况。

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