非整倍体作为睾丸原位癌的标志物。
Aneuploidy as a marker for carcinoma-in-situ of the testis.
作者信息
Müller J, Skakkeboek N E, Lundsteen C
出版信息
Acta Pathol Microbiol Scand A. 1981 Jan;89(1):67-8. doi: 10.1111/j.1699-0463.1981.tb00190.x.
Abstract
A microspectrophotometric study of the DNA content of carcinoma-in-situ germ cells in the testes of eight infertile men revealed an aneuploid DNA distribution pattern. The results support the assumption that carcinoma-in-situ germ cells are of a malignant nature. The findings also indicate that the DNA content can be used to discriminate between carcinoma-in-situ germ cells and spermatogonia.
摘要
一项对8名不育男性睾丸原位癌生殖细胞DNA含量的显微分光光度研究显示出非整倍体DNA分布模式。这些结果支持原位癌生殖细胞具有恶性性质这一假设。研究结果还表明，DNA含量可用于区分原位癌生殖细胞和精原细胞。
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