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抗坏血酸与大鼠应激性溃疡

Ascorbic acid and stress ulcer in the rat.

作者信息

Glavin G B, Paré W P, Vincent G P

出版信息

J Nutr. 1978 Dec;108(12):1969-75. doi: 10.1093/jn/108.12.1969.

Abstract

Rats were orally administered ascorbic acid at a dose of 30 g/liter during either total starvation, partial starvation, the activity-stress ulcer procedure, or the restraint-cold procedure. In four experiments, ascorbic acid failed to exert significant protective action against stomach ulcer formation and, in fact, may have potentiated the ulcerogenic process.

摘要

在完全饥饿、部分饥饿、活动-应激性溃疡实验或束缚-寒冷实验过程中,给大鼠口服剂量为30克/升的抗坏血酸。在四项实验中,抗坏血酸未能对胃溃疡形成发挥显著的保护作用,事实上,它可能还增强了溃疡形成过程。

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