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药物对暴露于寒冷-束缚应激的大鼠的影响。

Effect of drugs on rats exposed to cold--restraint stress.

作者信息

Beattie D

出版信息

J Pharm Pharmacol. 1977 Dec;29(12):748-51. doi: 10.1111/j.2042-7158.1977.tb11454.x.

DOI:10.1111/j.2042-7158.1977.tb11454.x
PMID:22622
Abstract

The extent of protection afforded by over 40 drugs of various pharmacological groups against the development of gastric erosions induced in rats by a combination of cold and restraint has been investigated. Some drugs offered good protection, others had no effect on, or exacerbated, the lesions. Attempts are made to explain the mode of action of the protective drugs.

摘要

已对40多种不同药理类别的药物对寒冷与束缚联合诱导大鼠胃糜烂形成的保护程度进行了研究。一些药物提供了良好的保护作用，其他药物对损伤没有影响或使其恶化。已尝试解释具有保护作用药物的作用方式。

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