Ziparo E, Geremia R, Russo M A, Stefanini M
Am J Anat. 1980 Dec;159(4):385-8. doi: 10.1002/aja.1001590404.
The presence of surface-recognition mechanisms between somatic and germ cells of the seminiferous epithelium has been studied in the rat by an assay in vitro based on the ability of homogeneous populations of spermatogenic cells, at specific differentiative stages, to adhere to monolayers of cultured Sertoli cells. The results show that germ cells adhere specifically to Sertoli cells and that the adhesion is dependent on the differentiative stage of the germ cells. Pachytene spermatocytes show the highest ability to adhere and form typical junctional specializations with the underlying Sertoli cells, while round spermatids adhere much less to the substrate. The possible regulative role of a somatic cell-germ interaction is discussed.
通过一项体外试验，基于特定分化阶段的生精细胞同质群体粘附于培养的支持细胞单层的能力，研究了大鼠生精上皮体细胞与生殖细胞之间表面识别机制的存在情况。结果表明，生殖细胞能特异性地粘附于支持细胞，且这种粘附依赖于生殖细胞的分化阶段。粗线期精母细胞表现出最高的粘附能力，并与下方的支持细胞形成典型的连接特化结构，而圆形精子细胞对底物的粘附则少得多。文中讨论了体细胞 - 生殖细胞相互作用可能的调节作用。
