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Detection of gangliosides that bind cholera toxin: direct binding of 125I-labeled toxin to thin-layer chromatograms.

作者信息

Magnani J L, Smith D F, Ginsburg V

出版信息

Anal Biochem. 1980 Dec;109(2):399-402. doi: 10.1016/0003-2697(80)90667-3.

DOI:10.1016/0003-2697(80)90667-3
PMID:7224165
Abstract
摘要

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Detection of gangliosides that bind cholera toxin: direct binding of 125I-labeled toxin to thin-layer chromatograms.结合霍乱毒素的神经节苷脂的检测:125I标记毒素与薄层层析图的直接结合
Anal Biochem. 1980 Dec;109(2):399-402. doi: 10.1016/0003-2697(80)90667-3.
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Characterization of the cholera toxin receptor on Balb/c 3T3 cells as a ganglioside similar to, or identical with, ganglioside GM1. No evidence for galactoproteins with receptor activity.将Balb/c 3T3细胞上的霍乱毒素受体鉴定为一种与神经节苷脂GM1相似或相同的神经节苷脂。没有证据表明存在具有受体活性的半乳糖蛋白。
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A sensitive method to quantitate gangliosides of the gangliotetraose series directly on chromatograms using peroxidase conjugated cholera toxin.
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Organization of ganglioside GM1 in phosphatidylcholine bilayers.神经节苷脂GM1在磷脂酰胆碱双分子层中的组织形式。
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Ganglioside localization on myelinated nerve fibres by cholera toxin binding.通过霍乱毒素结合定位神经节苷脂在有髓神经纤维上的位置。
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Fluorescent derivatives of ganglioside GM1 function as receptors for cholera toxin.神经节苷脂GM1的荧光衍生物可作为霍乱毒素的受体。
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Direct thin-layer chromatography of gangliosides of a total lipid extract.总脂质提取物中神经节苷脂的直接薄层色谱法。
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