Bierwolf D
Arch Geschwulstforsch. 1980;50(6):506-14.
The present state of tumor virus research in man is analysed in order to evaluate the cancer risk by viruses in man. For most of the viruses isolated from human tumorous or normal tissues and similar to oncogenic viruses of animals the participation as causative agent in the multifactorial process of cancer induction, promotion and realization in man is not yet established. This holds true for DNA viruses (paillomaviruses, SV 40-related viruses, Herpesvirus 2, hepatitis B virus) as well as for the retroviruses. There are, however, data which give circumstantial evidence for the association of members of these groups of viruses with certain types of human tumors. The foremost candidate as human tumor virus is the Epstein-Barr virus--an essential causative factor for Burkitt's lymphoma and nasopharyngeal carcinomas.
为了评估人类因病毒而患癌症的风险，对人类肿瘤病毒研究的现状进行了分析。从人类肿瘤组织或正常组织中分离出的、与动物致癌病毒相似的大多数病毒，作为人类癌症诱发、促进和发展这一多因素过程中的致病因子，其作用尚未得到证实。DNA病毒（乳头瘤病毒、SV40相关病毒、疱疹病毒2型、乙型肝炎病毒）以及逆转录病毒都是如此。然而，有数据间接证明这些病毒组的成员与某些类型的人类肿瘤有关联。作为人类肿瘤病毒的首要候选者是爱泼斯坦-巴尔病毒——伯基特淋巴瘤和鼻咽癌的一个重要致病因素。
