Pate E F, Brokaw C J
Biophys Struct Mech. 1980;7(1):51-63. doi: 10.1007/BF00538158.
Properties of the rigor state in muscle can be explained by a simple cross-bridge model, of the type which has been suggested for active muscle, in which detachment of cross-bridges by ATP is excluded. Two attached cross-bridge states, with distinct force vs. distortion relationships, are required, in addition to a detached state, but the attached cross-bridge states in rigor muscle appear to differ significantly from the attached cross-bridge states in active muscle. The stability of the rigor force maintained in muscle under isometric conditions does not require exceptional stability of the attached cross-bridges, if the positions in which attachment of cross-bridges is allowed are limited so that the attachment of cross-bridges in positions which have minimum free energy is excluded. This explanation of the stability of the rigor state may also be applicable to the maintenance of stable rigor waves on flagella.
肌肉中僵直状态的特性可用一种简单的横桥模型来解释，这种模型与已提出的用于活动肌肉的模型类型相同，其中ATP使横桥分离的情况被排除在外。除了分离状态外，还需要两种附着的横桥状态，它们具有不同的力与变形关系，但僵直肌肉中的附着横桥状态似乎与活动肌肉中的附着横桥状态有显著差异。如果允许横桥附着的位置受到限制，从而排除在具有最小自由能位置的横桥附着，那么在等长条件下肌肉中维持的僵直力的稳定性并不需要附着横桥具有特殊的稳定性。对僵直状态稳定性的这种解释也可能适用于鞭毛上稳定的僵直波的维持。
