十二指肠灌注牛奶、酪蛋白、乳糖和脂肪对喂牛奶犊牛胃排空和胃酸分泌的影响。
The effect of duodenal infusion of milk, casein, lactose and fat on gastric emptying and acid secretion in the milk-fed calf.
作者信息
Bell F R, McLeay L M
出版信息
J Physiol. 1978 Sep;282:51-7. doi: 10.1113/jphysiol.1978.sp012447.
Abstract
- The effect of infusion of the duodenum with milk, casein, lactose and fat on gastric acid secretion and abnormal emptying of a saline meal was studied in milk-fed calves. 2. Compared with sodium bicarbonate, infusion with casein or lactose, alone or together, caused a small but statistically significant slowing of gastric emptying but did not effect gastric acid secretion. 3. Infection of the duodenum with cows' milk replacer or bovine milk fat slowed gastric emptying markedly and reduced gastric acid secretion significantly below levels obtained with sodium bicarbonate infusion. 4. The experiments provide evidence for the existence of mechanisms which prevent the passage of substantial amounts of whole milk into the duodenum before it has been subjected to gastric digestion.
摘要
- 在以牛奶喂养的犊牛中，研究了向十二指肠输注牛奶、酪蛋白、乳糖和脂肪对胃酸分泌及生理盐水餐异常排空的影响。2. 与碳酸氢钠相比，单独或联合输注酪蛋白或乳糖会导致胃排空略有减慢，但具有统计学意义，且对胃酸分泌无影响。3. 用代乳品或牛乳脂肪感染十二指肠会显著减慢胃排空，并使胃酸分泌明显低于输注碳酸氢钠时的水平。4. 这些实验为以下机制的存在提供了证据，即在全脂牛奶未经胃消化之前，这些机制可防止大量全脂牛奶进入十二指肠。
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