Enright A C, Smith G G, Wyant G M
Can Anaesth Soc J. 1980 Nov;27(6):553-5. doi: 10.1007/BF03006884.
In a double blind study, seven volunteers were given lidocaine 0.75 per cent and bupivacaine 0.25 per cent in two trials to compare the agents for use in intravenous regional analgesia. There was no significant difference between the two agents in the duration of analgesia after removal of the tourniquet. Bupivacaine produced fewer side effects. It also consistently produced persistent analgesia on the posterolateral aspect of the forearm.
在一项双盲研究中,七名志愿者在两项试验中分别接受了0.75%的利多卡因和0.25%的布比卡因,以比较这两种药物用于静脉区域镇痛的效果。松开止血带后,两种药物的镇痛持续时间没有显著差异。布比卡因产生的副作用较少。它还在前臂后外侧持续产生持久的镇痛效果。