Godkin J D, Coté C, Duby R T
J Reprod Fertil. 1978 Nov;54(2):375-8. doi: 10.1530/jrf.0.0540375.
Preimplantation embryos, recovered from sheep on Days 13-15 of pregnancy, were incubated with luteal tissue from cyclic ewes. Extracts of ovine embryos were incubated with luteal tissue from cyclic Holstein cows. Embryos and embryo extracts significantly increased progesterone production by ovine and bovine luteal tissue in vitro. The embryos themselves did not produce measurable amounts of progesterone. We suggest that the ovine preimplantation embryo produces a substance with luteotrophic properties which contributes to the maintenance of early pregnancy.
从怀孕13 - 15天的绵羊体内回收的植入前胚胎，与发情周期母羊的黄体组织一起孵育。绵羊胚胎提取物与发情周期荷斯坦奶牛的黄体组织一起孵育。胚胎和胚胎提取物在体外显著增加了绵羊和牛黄体组织的孕酮分泌量。胚胎本身不产生可测量量的孕酮。我们认为，绵羊植入前胚胎产生一种具有促黄体生成特性的物质，这有助于维持早期妊娠。
