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用于脊髓灰质炎疫苗生产的食蟹猴培育。

Breeding of Macaca fascicularis for poliovaccine production.

作者信息

Boot R, Kruijt B C, van Steenis G, van Wezel A L

出版信息

Dev Biol Stand. 1981;47:15-8.

PMID:7227650
Abstract

In our Institute Cynomolgus monkeys (M. fascicularis) are mainly used for production and control of poliovaccine. In 1974 a small individual breeding colony was started. Last year the colony was enlarged with 10 harem groups. Based on colony reproduction data, group breeding seems more successful than individual breeding. Owing to developments in the production of poliovaccine, a state of total self supply is within reach. However attention must be paid to factors reducing breeding results, comprising aggressive interactions and disturbed mother-care. Finally replacement of breeding stock might require rearing conditions which are not compatible with those necessary for the establishment of a Foamy virus and Herpes-B virus breeding colony.

摘要

在我们研究所,食蟹猴(M. fascicularis)主要用于脊髓灰质炎疫苗的生产和质量控制。1974年开始建立了一个小型个体繁殖群体。去年,该群体扩大了10个一夫多妻制群体。根据群体繁殖数据,群体繁殖似乎比个体繁殖更成功。由于脊髓灰质炎疫苗生产的发展,实现完全自给自足的状态指日可待。然而,必须注意降低繁殖结果的因素,包括攻击性相互作用和受干扰的母性照料。最后,繁殖种群的替换可能需要与建立泡沫病毒和B型疱疹病毒繁殖群体所需的饲养条件不相容的饲养条件。

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