Nakafuji H, Koike Y, Wakabayashi M, Furihata R, Maruyama Y, Ogata H
Gastroenterol Jpn. 1981;16(2):134-40. doi: 10.1007/BF02774387.
Three cases of early stage carcinoma of the gallbladder are reported. In two cases, radiolucent shadow was demonstrated on cholecystogram. The masses were papillary adenomas with foci of adenocarcinoma. In the third case, the cholecystogram did not reveal particular findings except for shadows of numerous tiny gallstones. The malignancy was completely unexpected clinically, even after gross inspection of the organ. It was an incidental finding of microscopic examination, which disclosed abundant Rokitansky-Aschoff's sinuses associated with foci of cytologically malignant cells in the muscular layer. It was explained as malignant change of epithelium on one of the sinuses. All three patients underwent simple cholecystectomy. So far they have been free from evidence of metastasis or recurrence. The diagnosis and treatment of early carcinoma of the gallbladder are discussed.
报告了3例早期胆囊癌病例。其中2例在胆囊造影上显示出透光阴影。肿块为伴有腺癌灶的乳头状腺瘤。第3例中，胆囊造影除了众多微小胆结石的阴影外未发现特殊表现。临床上，即使在对该器官进行大体检查后，恶性肿瘤也完全出乎意料。这是显微镜检查的偶然发现，显示出大量罗-阿窦（Rokitansky-Aschoff窦），伴有肌层内细胞学上恶性细胞灶。其被解释为其中一个窦的上皮发生了恶性变化。所有3例患者均接受了单纯胆囊切除术。到目前为止，他们均无转移或复发迹象。文中讨论了早期胆囊癌的诊断和治疗。
