Possinger K, Hartenstein R, Ehrhart H
Fortschr Med. 1981 Mar 26;99(12):419-23.
The classic triad of hematuria, pain and presence of a palpable flank mass is found only in few patients with renal carcinoma. Hematuria, the main symptom, occurs in nearly the half of patients. Blood levels of erythropoetin and renin are often elevated and may be of value as biochemical tumor markers. Chemotherapeutic agents do not alter the course of metastatic renal carcinoma significantly. Vinblastine is the most effective available drug currently. Progestins or androgens cause tumor regression very seldom. If antioestrogens or immuntherapeutic regimens may improve therapeutic results, is not to be decided at present.
血尿、疼痛和可触及的侧腹肿块这一典型三联征仅在少数肾癌患者中出现。血尿是主要症状,近半数患者会出现。促红细胞生成素和肾素的血液水平常升高,可能作为生化肿瘤标志物有一定价值。化疗药物对转移性肾癌的病程影响不大。长春碱是目前最有效的可用药物。孕激素或雄激素很少能使肿瘤消退。抗雌激素或免疫治疗方案是否能改善治疗效果,目前尚无定论。