瑞典北部的人群研究。X. MN血型

Population studies in northern Sweden. X. The MN blood groups.

作者信息

Cedergren B, Nordenson I, Beckman L

出版信息

Hum Hered. 1981;31(2):100-3. doi: 10.1159/000153186.

Abstract

Frequencies of the MN blood groups were studied in a material of 3,312 conscripts and blood donors from the counties of Norrbotten and Västerbotten in northern Sweden. The individuals were distributed according to place of birth into 23 subpopulations. The frequency of the M gene was significantly higher in Norrbotten county than in Västerbotten county. The overall picture of geographical variation was, however, not explainable in terms of Lappish and Finnish influence. In Västerbotten county a significant departure from the Hardy-Weinberg equilibrium (excess of heterozygotes) was found. The inbreeding coefficient FST was found to be high (5.3 . 10(-3)) and significant (p less than 0.001) in Västerbotten county, but low (1.2 . 10(-3) and statistically not significance in Norrbotten county.

摘要

对瑞典北部北博滕郡和西博滕郡的3312名应征入伍者和献血者的材料进行了MN血型频率研究。这些个体根据出生地被分为23个亚群。北博滕郡的M基因频率显著高于西博滕郡。然而，地理变异的总体情况无法用拉普人和芬兰人的影响来解释。在西博滕郡发现了显著偏离哈迪-温伯格平衡（杂合子过多）的情况。发现西博滕郡的近交系数FST很高（5.3×10⁻³）且具有统计学意义（p<0.001），而北博滕郡的近交系数较低（1.2×10⁻³）且在统计学上无显著意义。