瑞典北部的人群研究。十三。6-磷酸葡萄糖酸脱氢酶多态性。
Population studies in northern Sweden. XIII. The 6-phosphogluconate dehydrogenase polymorphism.
作者信息
Beckman L, Beckman G, Nylander P O
机构信息
Department of Medical Genetics, University of Umeå, Sweden.
出版信息
Hum Hered. 1988;38(3):168-73. doi: 10.1159/000153779.
Frequencies of the 6-phosphogluconate dehydrogenase (6-PGD) genes were studied in a series of 314 Finns from northern Finland and in a material of 4,348 conscripts and blood donors from the counties of Norrbotten and Västerbotten in northern Sweden. The Swedish individuals were distributed into 23 subpopulations according to place of birth. The frequency of the PGDC gene was comparatively high in Finns (5.3%) and showed significant variations between subpopulations (from 5.3 to 0.0%). The frequency of the PGDC gene showed a cline, with a decreasing gene frequency in the north-south direction. This geographical pattern could be explained in terms of Lappish and Finnish influence.
在来自芬兰北部的314名芬兰人以及来自瑞典北部北博滕郡和西博滕郡的4348名应征入伍者和献血者中，研究了6 - 磷酸葡萄糖酸脱氢酶（6 - PGD）基因的频率。瑞典个体根据出生地被分为23个亚群。PGDC基因在芬兰人中的频率相对较高（5.3%），并且在亚群之间显示出显著差异（从5.3%到0.0%）。PGDC基因的频率呈现出一种渐变群，基因频率在南北方向上递减。这种地理模式可以用拉普人和芬兰人的影响来解释。
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