瑞典北部的人群研究。第十六部分。GC亚型。

Population studies in northern Sweden. XVI. GC subtypes.

作者信息

Nylander P O, Beckman L

机构信息

Department of Medical Genetics, University of Umeå, Sweden.

出版信息

Hum Hered. 1989;39(4):230-9. doi: 10.1159/000153865.

DOI:10.1159/000153865

PMID:2583736

Abstract

The frequencies of group-specific component (GC) subtypes were studied in a population of 4,053 conscripts and blood donors from the counties of Västerbotten and Norrbotten in northern Sweden. The individuals were distributed according to place of birth into 23 subpopulations. A significant heterogeneity between the 23 regions was observed for the GC1F, GC1S and GC2 genes, and clines were found for all genes. The frequency of the GC1F gene was increasing in the northern direction, and the frequencies of the GS1S and GC2 genes were increasing in the southern direction. The geographical pattern of the GC*1F gene frequency could be explained in terms of Lappish influence.

摘要

在瑞典北部韦斯特博滕郡和北博滕郡的4053名应征入伍者和献血者群体中，研究了群体特异性成分（GC）亚型的频率。这些个体根据出生地被分为23个亚群体。观察到GC1F、GC1S和GC2基因在这23个地区之间存在显著的异质性，并且所有基因都呈现出渐变群。GC1F基因的频率在向北的方向上增加，而GS1S和GC2基因的频率在向南的方向上增加。GC*1F基因频率的地理模式可以用拉普人的影响来解释。