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石棉相关病理学的临床与放射学观察

Clinical and radiological observations on asbestos-related pathology.

作者信息

Bohlig H, Hain E

出版信息

IARC Sci Publ. 1980(30):497-506.

PMID:7228304
Abstract

The papers in this session, which are summarized briefly, do not cover the wide range of radiological and clinical problems resulting from inhalation of asbestos dust. Pleural effusions are found in persons exposed occupationally to asbestos, even in the absence of asbestosis, but they are difficult to attribute to such exposure. Asbestosis of the lung shows no striking symptoms and can also be diagnosed only after all other possibilities have been excluded. There are no convincing or striking morphological peculiarities that suggest that an 'asbestos lung cancer' exists. Mesotheliomas of the pleura and of the peritoneum are usually resistant to therapy of any kind, although several possibilities are discussed. Radiological surveillance is presented as being still the most effective and reliable method for medical surveillance of asbestos workers. Circumscribed pleural thickening is benign but a good indicator of exposure to mineral dusts. Diffuse pleural thickening occurs frequently in nonexposed groups and cannot, therefore, be used as an indication of exposure; however, it cannot yet be ruled out as being significant epidemiologically.

摘要

本次会议的论文简要总结如下,并未涵盖吸入石棉粉尘所导致的广泛放射学和临床问题。职业性接触石棉的人群中会出现胸腔积液,即便没有石棉肺,但很难将其归因于这种接触。肺部石棉沉着病没有明显症状,而且也只有在排除所有其他可能性之后才能确诊。没有令人信服或显著的形态学特征表明存在“石棉肺癌”。胸膜和腹膜间皮瘤通常对任何治疗都有抵抗性,不过文中讨论了几种治疗可能性。放射学监测被认为仍是对石棉工人进行医学监测最有效且可靠的方法。局限性胸膜增厚是良性的,但却是接触矿物粉尘的良好指标。弥漫性胸膜增厚在未接触人群中也经常出现,因此不能用作接触指标;然而,从流行病学角度来看,尚不能排除其具有重要意义。

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