Braun-Falco O, Dorn M, Neubert U, Plewig G
Hautarzt. 1981 Jan;32(1):17-22.
Trachyonychia (20-nail dystrophy) is described in four patients with clinical, histological, and scanning electron microscopy techniques. Trachyonychia is a polyetiological symptom: psoriasis vulgaris, lichen planus, alopecia areata, atopic dermatitis, 20-nail dystrophy of childhood, and severe nail dystrophy can all lead to trachyonychia-like nail changes. Nail bed biopsies are necessary for proper diagnosis. In our patients, lichen planus, or psoriasis were excluded clinically and histologically. Spongiotic dermatitis of nail matrix and nail bed with column-like parakeratosis within the nail plate are found in trachyonychia due to alopecia areata, atopic dermatitis, and in its idiopathic form.
我们运用临床、组织学和扫描电子显微镜技术，对4例患者的20甲营养不良（糙甲症）进行了描述。糙甲症是一种多病因症状：寻常型银屑病、扁平苔藓、斑秃、特应性皮炎、儿童20甲营养不良以及严重的甲营养不良均可导致类似糙甲症的甲改变。进行正确诊断需要做甲床活检。在我们的患者中，临床上和组织学上均排除了扁平苔藓或银屑病。斑秃、特应性皮炎及其特发性形式所致的糙甲症，可见甲母质和甲床的海绵状皮炎，甲板内有柱状角化不全。
