吸入性糖皮质激素对乙酰甲胆碱气道反应性的影响。
Effect of an inhaled corticosteroid on methacholine airway reactivity.
作者信息
Easton J G
出版信息
J Allergy Clin Immunol. 1981 May;67(5):388-90. doi: 10.1016/0091-6749(81)90084-1.
PMID:7229227
Abstract
Methacholine airway reactivity was studied in seven asthmatic patients before and at the end of 4 mo of beclomethasone dipropionate therapy, as well as in a control group. There was no statistically significant change in reactivity in either group, suggesting that a change in airway cholinergic receptor activity is not part of the mechanism of action of corticosteroids in asthma.
摘要
在七名哮喘患者中，于丙酸倍氯米松治疗4个月之前及结束时研究了乙酰甲胆碱气道反应性，同时还设立了一个对照组。两组的反应性均无统计学上的显著变化，这表明气道胆碱能受体活性的改变并非皮质类固醇治疗哮喘作用机制的一部分。
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