Hafeez M, Rao B V
J Helminthol. 1981 Mar;55(1):29-32.
The life span and the pathogenicity of amphistomes developing from Cercariae indicae XXVI (Paramphistomum epicilitum) were considerably reduced when the metacercariae were gamma-irradiated at 2 krad or 3 krad. The higher irradiation dose resulted in the complete absence of the flukes in infected animals. Single vaccination of lambs and kids with 3000 metacercariae irradiated at 2 krad or 3 krad stimulated a significant degree of resistance against challenge with 5000 non-irradiated metacercariae. The resistance was more pronounced in the group vaccinated with metacercariae irradiated at 3 krad.
