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慢性酒精中毒患者的糙皮病:20例尸检病例的临床与病理研究

Pellagra among chronic alcoholics: clinical and pathological study of 20 necropsy cases.

作者信息

Ishii N, Nishihara Y

出版信息

J Neurol Neurosurg Psychiatry. 1981 Mar;44(3):209-15. doi: 10.1136/jnnp.44.3.209.

Abstract

Twenty cases of pellagra, diagnosed on neuropathological grounds, were found amont 74 necropsy cases of chronic alcoholism. Although these patients had presented with various mental, neurological and gastrointestinal symptoms, the diagnosis of pellagra had not been established clinically because, in the majority, there were no skin lesions. It is emphasised that whenever chronic alcoholics exhibit certain mental, neurological or gastrointestinal symptoms, one should strongly suspect pellagra even in the absence of skin lesions (pellagra sine pelle agra).

摘要

在74例慢性酒精中毒尸检病例中,发现20例基于神经病理学诊断为糙皮病。尽管这些患者表现出各种精神、神经和胃肠道症状,但临床上未确诊为糙皮病,因为大多数患者没有皮肤病变。需要强调的是,每当慢性酒精中毒患者出现某些精神、神经或胃肠道症状时,即使没有皮肤病变(无皮肤糙皮病),也应高度怀疑糙皮病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fd4/490893/a38c833dda6e/jnnpsyc00059-0030-a.jpg

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