Chen S C, Donahoe J L, Fagan L F
Jpn Heart J. 1981 Mar;22(2):167-72. doi: 10.1536/ihj.22.167.
Eighty-nine children with rheumatic fever between 1964 and 1978 were reviewed. There were 40 males and 49 females. The first attack occurred mostly between 6 and 12 years. Arthritis was present in 62.9%; carditis, 55.1%; chorea, 19.1%. Children were followed from 20 months to 15 years (mean 61 months). Seventeen developed current attacks (19.1%). On final examination, 40 had no heart disease, 30 had mild heart disease, 6 required valve surgery, 4 had died, and 9 had moderate heart disease but not operated. Chorea was present in 20 children. Six of them also had mitral insufficiency, 3 had recurrence after episode of chorea. Prompt diagnosis and treatment of streptococcal infection and penicillin prophylaxis need to be stressed. Service carditis on initial attack and recurrence predispose to the development of severe heart disease.
对1964年至1978年间的89例风湿热患儿进行了回顾性研究。其中男性40例，女性49例。首次发病多在6至12岁之间。关节炎发生率为62.9%；心脏炎为55.1%；舞蹈病为19.1%。对患儿随访了20个月至15年（平均61个月）。17例出现了近期发作（19.1%）。在最后检查时，40例无心脏病，30例有轻度心脏病，6例需要进行瓣膜手术，4例死亡，9例有中度心脏病但未手术。20例患儿出现舞蹈病。其中6例还伴有二尖瓣关闭不全，3例在舞蹈病发作后复发。需要强调对链球菌感染进行及时诊断和治疗以及青霉素预防。初次发作和复发时的心脏炎易导致严重心脏病的发生。
