Vlietstra R E, Holmes D R, Smith H C, Hartzler G O, Orszulak T A
Mayo Clin Proc. 1981 May;56(5):287-93.
Percutaneous transluminal coronary angioplasty is a promising new method of treatment for patients with coronary artery disease. Inflation of a balloon located at the tip of a catheter is used to dilate stenoses. In the first year of the use of percutaneous transluminal coronary angioplasty at the Mayo Clinic, it was applied in 34 selected patients whose severe angina pectoris was related to a single, high-grade coronary artery stenosis. Successful dilation (stenosis opened by 40% or more of the normal luminal diameter) was achieved in 22 patients (65% of the total). Early postangioplasty assessment indicated relief of angina in all of these patients except for one patient who demonstrated coronary spasm that was responsive to medication. Median hospital stay was 3 days. Failure of percutaneous transluminal coronary angioplasty in the remaining 12 patients was usually due to an inability to manipulate the balloon catheter across the stenotic segment. Eleven of these patients had saphenous vein bypass graft surgery, as planned, immediately after the attempted angioplasty. There have been no deaths, but three patients sustained a transmural myocardial infarction. This initial experience with percutaneous transluminal coronary angioplasty indicates that it is a relatively safe and a frequently effective method of relieving coronary stenosis in selected patients with symptomatic coronary artery disease.
经皮腔内冠状动脉成形术是治疗冠心病患者的一种有前景的新方法。通过充盈位于导管顶端的球囊来扩张狭窄部位。在梅奥诊所使用经皮腔内冠状动脉成形术的第一年，该方法应用于34例经挑选的患者，这些患者的严重心绞痛与单一的、高度冠状动脉狭窄有关。22例患者（占总数的65%）成功实现扩张（狭窄部位的管腔直径扩大至正常直径的40%或更多）。血管成形术后的早期评估显示，除1例出现对药物有反应的冠状动脉痉挛患者外，所有这些患者的心绞痛均得到缓解。中位住院时间为3天。其余12例患者经皮腔内冠状动脉成形术失败通常是由于无法将球囊导管穿过狭窄段。其中11例患者按计划在尝试血管成形术后立即进行了大隐静脉旁路移植手术。无死亡病例，但有3例患者发生了透壁性心肌梗死。经皮腔内冠状动脉成形术的这一初步经验表明，对于有症状的冠心病患者，它是一种相对安全且经常有效的缓解冠状动脉狭窄的方法。
