Horita N, Matsushita M, Ishii T, Oyanagi S, Sakamoto K
Neuropathol Appl Neurobiol. 1981 Mar-Apr;7(2):97-102. doi: 10.1111/j.1365-2990.1981.tb00079.x.
In a case of hepatocerebral disease of Inose type the astrocytes, corresponding to Alzheimer type II glia, had swollen cytoplasm containing glycogen granules and focal aggregates of lipofuscin granules. Their nuclei contained bodies of simple and of complex types as well as conglomerates of glycogen granules without any capsules. The nuclear bodies of simple type were also observed in the nuclei of endothelial cells. It is concluded that these changes in the appearance of Alzheimer type II glia suggest reactive and defensive changes in the brain against ammonium ions, rather than being merely degenerative in nature.
在一例稻野型肝脑疾病中，与阿尔茨海默II型神经胶质细胞相对应的星形胶质细胞，其细胞质肿胀，含有糖原颗粒和脂褐素颗粒的局灶性聚集物。它们的细胞核含有简单型和复合型包涵体以及无包膜的糖原颗粒聚集体。在内皮细胞核中也观察到了简单型核包涵体。得出的结论是，阿尔茨海默II型神经胶质细胞外观的这些变化表明大脑对铵离子的反应性和防御性变化，而不仅仅是退行性变化。
