Jansen J B, Lamers C B
Regul Pept. 1981 Mar;1(6):415-21. doi: 10.1016/0167-0115(81)90044-6.
The effect of intravenously administered calcitonin and secretin on bombesin-stimulated serum gastrin and gastric acid secretion was studied on 7 volunteers. Secretin G.I.H. (1 C.U./kg per h) and calcitonin (0.5 I.U./kg per h) significantly (P less than 0.05) inhibited the serum gastrin and gastric acid responses to bombesin-14 (90 pmol/kg per h). Inhibition of gastrin release could not fully account for the inhibition of gastric acid secretion.
对7名志愿者研究了静脉注射降钙素和促胰液素对蛙皮素刺激的血清胃泌素及胃酸分泌的影响。促胰液素(胃肠激素)(每小时1单位/千克)和降钙素(每小时0.5国际单位/千克)显著(P<0.05)抑制了对蛙皮素-14(每小时90皮摩尔/千克)的血清胃泌素及胃酸反应。胃泌素释放的抑制不能完全解释胃酸分泌的抑制。