用阿齐美克恢复无反应性癌症患者的免疫功能。

Immunorestoration of anergic cancer patients by azimexon.

作者信息

Goutner A, Nasrat F, Bonardelle D, Rameau G

出版信息

Recent Results Cancer Res. 1980;75:47-52. doi: 10.1007/978-3-642-81491-4_8.

Abstract

Azimexon, a new synthetic immunoadjuvant, can act on delayed-type hypersensitivity (DTH) reactions. Seven of 11 anergic cancer patients have been immunorestored by a relatively low dosage of azimexon. The effect on the lymphocyte responsiveness, and particularly of a new T-lymphocyte mitogen (TPA), are described. The possible mechanisms of the anergy of the cancer patients and of the mode of action of azimexon are discussed.

摘要

氮氧苯唑啉，一种新型合成免疫佐剂，可作用于迟发型超敏反应（DTH）。11名无反应性癌症患者中有7名通过相对低剂量的氮氧苯唑啉实现了免疫恢复。文中描述了其对淋巴细胞反应性的影响，特别是对一种新型T淋巴细胞有丝分裂原（TPA）的影响。还讨论了癌症患者无反应性的可能机制以及氮氧苯唑啉的作用方式。