猫睡眠期间视前区-下丘脑前部电刺激对呼吸的影响。

Respiratory effects of preoptic-anterior hypothalamic electrical stimulation during sleep in cats.

作者信息

Parmeggiani P L, Calasso M, Cianci T

出版信息

Sleep. 1981;4(1):71-82. doi: 10.1093/sleep/4.1.71.

DOI:10.1093/sleep/4.1.71

Abstract

The respiratory effects of preoptic-anterior hypothalamic (PO-AH) and vagal repetitive electrical stimulation (RES) were studied in unrestrained cats during sleep. PO-AH RES influenced breathing consistently during synchronized sleep but only occasionally during desynchronized sleep. Induction of desynchronized sleep by PO-AH RES was also observed. The respiratory effects of PO-AH RES on one side were enhanced by concomitant PO-AH warming on the other side during synchronized sleep but not during desynchronized sleep. Breathing was affected by vagal RES during both sleep stages, although an increase in threshold and in variability of respiratory responses was apparent during the latter sleep stage. The results show that PO-AH unresponsiveness during desynchronized sleep is nonspecific.

摘要

在睡眠状态下，对未受束缚的猫进行视前区-下丘脑前部（PO-AH）和迷走神经重复电刺激（RES）的呼吸效应研究。PO-AH RES在同步睡眠期间持续影响呼吸，但在非同步睡眠期间仅偶尔产生影响。还观察到PO-AH RES诱导非同步睡眠。在同步睡眠期间，另一侧的PO-AH升温会增强同侧PO-AH RES对呼吸的影响，但在非同步睡眠期间则不会。在两个睡眠阶段，迷走神经RES均会影响呼吸，尽管在后一个睡眠阶段呼吸反应的阈值和变异性明显增加。结果表明，非同步睡眠期间PO-AH无反应是非特异性的。