Parmeggiani P L, Azzaroni A, Cevolani D, Ferrari G
Electroencephalogr Clin Neurophysiol. 1986 Mar;63(3):289-95. doi: 10.1016/0013-4694(86)90096-9.
Thermal responsiveness of anterior hypothalamic-preoptic (AH-PO) neurons was studied in unanesthetized sleeping cats carrying chronically implanted electrodes and thermistors for recording EEG, EMG and AH-PO temperature. Activity of AH-PO neurons was recorded using tungsten microelectrodes during atraumatic stereotaxic head restraint in a sound-attenuated chamber at 22-25 degrees C. Direct cooling or warning of the AH-PO region was accomplished with bilaterally positioned water-perfused thermodes. 110 thermosensitive neurons (77% cold-sensitive and 23% warm-sensitive) were sampled during wakefulness and synchronized sleep. In contrast, the changes in spontaneous firing rate shown by AH-PO neurons during desynchronized sleep were often associated with a strong depression or outright suppression of their responsiveness to AH-PO thermal stimulation.
在未麻醉的睡眠猫中研究了下丘脑前部视前区（AH-PO）神经元的热反应性，这些猫长期植入了电极和热敏电阻以记录脑电图（EEG）、肌电图（EMG）和AH-PO温度。在22-25摄氏度的隔音室内，使用钨微电极在无创伤立体定向头部固定期间记录AH-PO神经元的活动。通过双侧放置的水灌注热电极对AH-PO区域进行直接冷却或加热。在清醒和同步睡眠期间对110个热敏神经元（77%对冷敏感，23%对热敏感）进行了采样。相比之下，AH-PO神经元在去同步睡眠期间自发放电率的变化通常与其对AH-PO热刺激的反应性强烈降低或完全抑制有关。
