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15α-羟基-11-氧代孕酮转化为3β,11α,15β-三羟基-5-孕烯-20-酮。

Conversion of 15 alpha-hydroxy-11-oxo-progesterone to 3 beta, 11 alpha, 15 beta-trihydroxy-5-pregnen-20-one.

作者信息

Weihe G R, McMorris T C

出版信息

Steroids. 1981 Mar;37(3):291-301. doi: 10.1016/s0039-128x(81)90274-9.

DOI:10.1016/s0039-128x(81)90274-9
PMID:7233456
Abstract

3 beta, 11 alpha, 15 beta-Trihydroxy-5-pregnen-20-one, an intermediate required for the synthesis of the oogoniols, has been prepared from 15 alpha-hydroxy-11-oxoprogesterone in an overall yield of 16%. The three isomers (at C-11, C-15) of the pregnene were also prepared.

摘要

3β,11α,15β-三羟基-5-孕烯-20-酮是合成卵原醇所需的中间体，它由15α-羟基-11-氧代孕酮制备而成，总产率为16%。同时还制备了孕烯的三种异构体（C-11、C-15位）。

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