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[抗凝剂和纤维蛋白溶解制剂在急性胰腺炎辅助治疗中的重要性]

[Importance of anticoagulants and fibrinolytic preparations in the adjuvant treatment of acute pancreatitis].

作者信息

Klimov V N, Lisienko V M, Krasovskaia G A

出版信息

Vestn Khir Im I I Grek. 1981 Feb;126(2):120-3.

PMID:7233705
Abstract

The hemostasis system was investigated in 95 patients with edema of the pancreas (71) and pancreatonecrosis (24). The alterations found speak of the state of hypercoagulation and activation of aggregation properties of the blood in 74 % of patients with edema of the pancreas and in 80 % of patients with pancreatonecrosis. The data obtained enabled the authors to perform the pathogenetic treatment in 63,1 % of patients by means of anticoagulants of the direct and indirect action in combination with the desaggregative therapy activating fibrinolysis. The treatment was carried on in combination with the generally used methods of surgery and therapy. During the period under consideration there were no lethal outcomes in the group of patients subjected to conservative treatment. The postoperative lethality in pancreatonecrosis decreased from 31,8 % to 27,2 %.

摘要

对95例胰腺水肿患者(71例)和胰腺坏死患者(24例)的止血系统进行了研究。研究发现,74%的胰腺水肿患者和80%的胰腺坏死患者存在血液高凝状态和聚集特性激活。所获数据使作者能够对63.1%的患者采用直接和间接作用的抗凝剂联合激活纤维蛋白溶解的解聚疗法进行病因治疗。治疗与常用的手术和治疗方法相结合。在研究期间,接受保守治疗的患者组没有出现死亡病例。胰腺坏死患者的术后死亡率从31.8%降至27.2%。

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