[直肠癌局部照射中放射病理形态学的定量标准]
[Quantitative criteria of radiation pathomorphosis in focal irradiation of rectal cancer].
作者信息
Kanaev S V, Savel'eva O P, Serov S F, Mel'nikov R A, Frolova Z V
出版信息
Vopr Onkol. 1981;27(4):60-3.
One study group consisting of 22 patients received 4-5 focal doses of 6 Gy every other day (total dose--24-30 Gy, 1,400-1,600 NSD). There was a 15-20 day interval between radiation therapy commencement and surgery. Another 12 patients received 4 daily doses of 5 Gy (total dose--20 Gy, 1,140 NSD) and were operated on 24-48 hrs after irradiation. The oncolytic index was 36% plus or minus 4.8 in study group 1 and 21% plus or minus 4.4--in group 2 (P less than 0.05). Mitotic index in group 1 fell from 6.7 to 3.1%, while in group 2--to zero.
一个由22名患者组成的研究组每隔一天接受4至5次局部剂量的6戈瑞照射（总剂量为24至30戈瑞，1400至1600名义标准剂量）。放疗开始与手术之间间隔15至20天。另外12名患者每天接受4次5戈瑞的剂量照射（总剂量为20戈瑞，1140名义标准剂量），并在照射后24至48小时接受手术。研究组1的溶瘤指数为36%±4.8，研究组2为21%±4.4（P<0.05）。研究组1的有丝分裂指数从6.7%降至3.1%，而研究组2则降至零。
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