Fine J D, Miller J A, Harrist T J, Haynes H A
Am J Med. 1981 May;70(5):1133-5. doi: 10.1016/0002-9343(81)90888-3.
Cutaneous nodules are recognized as a manifestation of disseminated candidiasis. We describe skin lesions clinically identical to ecthyma gangrenosum that, on microscopic examination, were due to Candida emboli rather than Pseudomonas sepsis. Thus, the appearance of necrotic pustules and ulcerative plaques in the immunocompromised patient would raise the possibility of Candida as well as Pseudomonas sepsis, and illustrates the diagnostic importance of skin biopsy in such cases.
皮肤结节被认为是播散性念珠菌病的一种表现。我们描述了临床上与坏疽性脓皮病相同的皮肤病变,经显微镜检查,这些病变是由念珠菌栓子而非铜绿假单胞菌败血症引起的。因此,免疫功能低下患者出现坏死性脓疱和溃疡性斑块时,念珠菌和铜绿假单胞菌败血症均有可能,这说明了此类病例中皮肤活检的诊断重要性。