Kimball C D, Chang C M, Huang S M, Houck J C
Am J Obstet Gynecol. 1981 May 15;140(2):157-64. doi: 10.1016/0002-9378(81)90103-4.
Immunoreactive endorphin peptides (ir EP) and prolactin (PRL) were measured by radioimmunoassay in venous blood from the umbilical cord of 86 neonates, 23 postpartum mothers, and 40 randomly selected blood bank donor control subjects. We also assayed these hormones in serosanguineous placental tissue fluid following delivery. The data suggest both ir EP and PRL are elevated during both processes and that placental chemistry may be implicated in blood levels of these hormones. Some biological and clinical aspects of placental opiates are discussed.
采用放射免疫分析法测定了86例新生儿脐带血、23例产后母亲静脉血以及40例随机选取的血库供者对照者静脉血中的免疫反应性内啡肽（ir EP）和催乳素（PRL）。我们还在分娩后的胎盘血清样组织液中检测了这些激素。数据表明，在这两个过程中ir EP和PRL均升高，且胎盘化学物质可能与这些激素的血液水平有关。文中讨论了胎盘阿片类物质的一些生物学和临床方面的问题。
