Sweeny P R, Brown R G
Am J Pathol. 1981 May;103(2):201-9.
This paper presents an ultrastructural study of the changes occurring in the gastrocnemius tendon of normal and selenium-deficient ducklings from 1 to 12 days of age. The study revealed that the normal 1--8-day-old duckling tendon contained 2 morphologically distinct cell types and a third occurring at Days 8--12. The location of these cells within the endotendineum and fiber bundles and their morphologic characteristics are presented. Most cells showed cytologic alterations as early as 4 days on the deficient diet with progressive deterioration to Day 12. The various cell types showed a differential response to the deficiency. Changes included altered endoplasmic reticulum and Golgi apparatus and eventual cell rupture. The significance of these observations and their possible relationship to the etiology of selenium-deficiency-induced dystrophy is discussed.
本文呈现了对1至12日龄正常和缺硒雏鸭腓肠肌腱所发生变化的超微结构研究。该研究表明，正常1至8日龄雏鸭的肌腱包含两种形态上不同的细胞类型，第三种细胞类型出现在8至12日龄。文中介绍了这些细胞在内肌腱和纤维束中的位置及其形态特征。早在缺硒日粮喂养4天时，大多数细胞就出现了细胞学改变，并持续恶化至12日龄。不同细胞类型对缺硒的反应存在差异。变化包括内质网和高尔基体改变，最终细胞破裂。讨论了这些观察结果的意义及其与硒缺乏诱导的营养不良病因的可能关系。
