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[胚胎和胎儿细胞变性的荧光显微镜检查]

[Fluorescence microscopy on embryonic and fetal cell degeneration].

作者信息

Menkes B, Prelipceanu O, Căpălnăşan I

出版信息

Morphol Embryol (Bucur). 1977 Oct-Dec;23(4):247-51.

PMID:72354
Abstract

Fluorochromes (acridin orange, quinakrin, koriphosin, auramin) introduced into the embryonic or foetal blood stream induce in the normal areas of cell death an elective fluorescence, as attested by experiments carried out on chick and rat embryos and foetuses. This vital method may serve as an experimental model for investigations concerning the transfer from the mother to the embryo or foetus of teratogenic substances as well as of their persistance and distribution--under certain experimental conditions--within the organism of the embryo or foetus.

摘要

将荧光染料(吖啶橙、奎纳克林、科里福辛、金胺)注入胚胎或胎儿的血流中,在正常的细胞死亡区域会产生选择性荧光,这已在鸡和大鼠胚胎及胎儿上进行的实验中得到证实。这种活体方法可作为一种实验模型,用于研究致畸物质从母体向胚胎或胎儿的转移,以及在某些实验条件下这些物质在胚胎或胎儿体内的持续存在和分布情况。

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