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肠炎沙门氏菌韦尔泰夫雷德噬菌体类型的亚分类及采用扩展噬菌体分型方案对菌株进行分型

Sub-classification of phage types of Salmonella weltevreden and typing of strains by an extended phage typing scheme.

作者信息

Sood L R, Basu S

出版信息

Antonie Van Leeuwenhoek. 1980;46(5):467-73. doi: 10.1007/BF00395827.

Abstract

By the use of two adapted phage preparations of Typing phage II the S. weltevreden phage types 4 and 5 could be classified into two sub-types each and phage types 9 and 10 into three sub-types each. the 1094 strains of S. weltevreden could be classified into a total of sixteen phage types including the sub-types. The host range mutants of Typing phage II were distinct from the parent strain. After adaptation to two insensitive strains, one of the new preparations, phi IIA lost its affinity to some strains which were lysed by the parent phage strain but gained lytic affinity for a few others that were originally insensitive. The second preparation phi IIB showed an increase in lytic range as expected. Antigenically these preparations were shown to be related but not identical. The possible reasons for serological non-identity of host range mutants with the parent strain have been discussed.

摘要

通过使用两种经过改良的Ⅱ型分型噬菌体制剂,韦尔托夫登沙门氏菌的4型和5型噬菌体各可分为两个亚型,9型和10型噬菌体各可分为三个亚型。1094株韦尔托夫登沙门氏菌总共可分为包括这些亚型在内的16种噬菌体类型。Ⅱ型分型噬菌体的宿主范围突变体与亲代菌株不同。在适应两种不敏感菌株后,其中一种新制剂phi IIA失去了对一些能被亲代噬菌体菌株裂解的菌株的亲和力,但对一些原本不敏感的其他菌株获得了裂解亲和力。第二种制剂phi IIB的裂解范围如预期的那样有所增加。这些制剂在抗原性上显示出相关但不相同。已经讨论了宿主范围突变体与亲代菌株血清学不一致的可能原因。

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