Flohr K H, Weir E K, Chesler E
Br Heart J. 1981 May;45(5):577-82. doi: 10.1136/hrt.45.5.577.
Measurements made from carotid pulse tracings and phonocardiograms are helpful in the prediction of severe aortic stenosis in young patients. In the elderly, however, analysis of the carotid pulse tracing and, in particular, its maximum rate of rise has proved unreliable because the range of normal values for this age group has not been established. Consequently, we studied 44 young normal and 44 older normal subjects, 15 older patients with systolic hypertension, and 36 older patients with significant aortic stenosis. Measurements obtained from the carotid pulse included the left ventricular ejection time, upstroke time, half-rise time, and the maximum rate of rise. The peak of the systolic murmur in aortic stenosis was measured phonocardiographically from the Q wave of the simultaneously recorded electrocardiogram (QP interval). The results confirm that the maximum rate of rise of the carotid pulse of normal older subjects is much more rapid than that of young subjects. Among elderly patients with aortic stenosis, the maximum rate of rise falls within the range of the normal young. Measurement of the half-rise time is imprecise, and there is considerable overlap with the normal. This is also true of left ventricular ejection time. The upstroke time is unreliable because of wave distortion produced by the arteriosclerotic vascular bed. The two most valuable and easily recorded measurements are the maximum rate of rise and the QP interval. A maximum rate of rise of more than 1000 mmHg/s and a QP interval of less than 220 ms argue strongly against the diagnosis of severe aortic stenosis. These measurements provide a simple, non-invasive means of avoiding left heart catheterisation in older subjects suspected of having severe aortic stenosis.
通过颈动脉脉搏描记图和心音图进行的测量,有助于预测年轻患者的严重主动脉瓣狭窄。然而,在老年人中,对颈动脉脉搏描记图,尤其是其最大上升速率的分析已被证明不可靠,因为该年龄组的正常值范围尚未确定。因此,我们研究了44名年轻正常受试者、44名老年正常受试者、15名老年收缩期高血压患者和36名老年重度主动脉瓣狭窄患者。从颈动脉脉搏获得的测量值包括左心室射血时间、上升时间、半上升时间和最大上升速率。主动脉瓣狭窄时收缩期杂音的峰值通过心音图从同时记录的心电图的Q波(QP间期)进行测量。结果证实,正常老年受试者颈动脉脉搏的最大上升速率比年轻受试者快得多。在老年主动脉瓣狭窄患者中,最大上升速率落在正常年轻人的范围内。半上升时间的测量不准确,与正常情况有相当大的重叠。左心室射血时间也是如此。由于动脉硬化血管床产生的波形失真,上升时间不可靠。两个最有价值且易于记录的测量值是最大上升速率和QP间期。最大上升速率超过1000mmHg/s且QP间期小于220ms强烈反对重度主动脉瓣狭窄的诊断。这些测量提供了一种简单、无创的方法,可避免对疑似患有重度主动脉瓣狭窄的老年受试者进行左心导管检查。