Ighiyasu H, Craige E
Jpn Heart J. 1980 Jul;21(4):465-84. doi: 10.1536/ihj.21.465.
The morphology of the externally recorded carotid pulse tracing was studied in 33 patients with valvular aortic stenosis for indices of severity. Comparisons were made with 10 normal controls. In aortic stenosis, initial upstroke time (IUT) of the carotid pulse, and left ventricular ejection time index were significantly higher and the rate of rise of the carotid pulse was slower than in the control group. Severity of stenosis (calculated valve area and mean pressure gradient) could not be predicted, however, from any of these indices. The IUT of the carotid pulse did correlate well with mean velocity of circumferential fiber shortening (mVcf) (r=-0.72). The rate of rise of the carotid pulse had also a correlation with mVcf(r=0.66). However, other commonly used hemodynamic indices (cardiac index, systemic vascular resistance, stroke volume, and ejection fraction) did not have a good correlation with IUT and rate of rise of the carotid pulse. These results suggest that we are able to separate by carotid pulse tracings aortic stenosis from normal subjects, but we cannot say what is the degree of severity of aortic stenosis from analysis of the external carotid pulse recording.
对33例瓣膜性主动脉狭窄患者的外部记录的颈动脉脉搏描记图形态进行了研究,以评估严重程度指标。并与10名正常对照者进行了比较。在主动脉狭窄患者中,颈动脉脉搏的初始上升时间(IUT)和左心室射血时间指数显著高于对照组,且颈动脉脉搏的上升速率比对照组慢。然而,无法根据这些指标中的任何一项预测狭窄的严重程度(计算出的瓣膜面积和平均压力梯度)。颈动脉脉搏的IUT与圆周纤维缩短平均速度(mVcf)有很好的相关性(r=-0.72)。颈动脉脉搏的上升速率也与mVcf相关(r=0.66)。然而,其他常用的血流动力学指标(心脏指数、全身血管阻力、每搏量和射血分数)与颈动脉脉搏的IUT和上升速率没有良好的相关性。这些结果表明,我们能够通过颈动脉脉搏描记图将主动脉狭窄与正常受试者区分开来,但通过分析颈外动脉脉搏记录无法确定主动脉狭窄的严重程度。