直肠给药微灌肠剂后血清和唾液中8-甲氧基补骨脂素的水平。
Serum and saliva levels of 8-methoxypsoralen after rectal administration as a micro-enema.
作者信息
Stolk L, Siddiqui A H, Kammeyer A, Cormane R H, van Zwieten P A
出版信息
Br J Dermatol. 1981 Apr;104(4):447-51. doi: 10.1111/j.1365-2133.1981.tb15316.x.
Serum and saliva concentrations of 8-methoxypsoralen (8-MOP) were determined in seven healthy human volunteers after rectal administration of a micro-enema. High peak serum levels were reached very soon(0.7 + or - 0.3 h) after administration of 8-MOP. Nausea was not experienced. There was a reasonable good linear correlation between 8-MOP concentrations in saliva and serum (r = 0.937). The saliva/serum ratio for 8-MOP concentration was 0.08 +/- 0.02.
在七名健康人类志愿者经直肠给予微灌肠剂后，测定了血清和唾液中8-甲氧基补骨脂素（8-MOP）的浓度。给予8-MOP后很快（0.7±0.3小时）就达到了血清高峰浓度。未出现恶心症状。唾液和血清中8-MOP浓度之间存在合理的良好线性相关性（r = 0.937）。8-MOP浓度的唾液/血清比值为0.08±0.02。
Zotero 插件