Howard J K, Sabapathy N N, Whitehead P A
Br J Ind Med. 1981 May;38(2):110-6. doi: 10.1136/oem.38.2.110.
Tests of pulmonary function (FVC, FEV1, FEV 1%, and single breath CO diffusion), renal function (serum creatinine and BUN), liver function (serum ALT, AST, and ALKP) and a full haematological screen were performed on 27 paraquat spraymen (mean spraying time 5.3 years; mean individual annual quantity of paraquat handled, 67.2 kg as paraquat ion) and on two control groups. One of the control groups consisted of 24 general plantation workers with minimal exposure to paraquat arising from occasional work in recently sprayed areas, and the second consisted of 23 latex factory workers with no known occupational exposure to paraquat. The results showed no significant differences as a consequence of occupational exposure to paraquat. Long-term paraquat spraying at the concentrations used produced to quantifiable harmful effects on health as measured by the indices selected for this study.
对27名百草枯喷雾员（平均喷雾时间5.3年；平均每人每年处理的百草枯量为67.2千克百草枯离子）以及两个对照组进行了肺功能测试（用力肺活量、第一秒用力呼气量、第一秒用力呼气率和单次呼吸一氧化碳弥散量）、肾功能测试（血清肌酐和血尿素氮）、肝功能测试（血清谷丙转氨酶、谷草转氨酶和碱性磷酸酶）以及全血细胞检查。其中一个对照组由24名普通种植园工人组成，他们因偶尔在近期喷洒过百草枯的区域工作而接触到极少的百草枯；另一个对照组由23名乳胶厂工人组成，他们没有已知的职业性百草枯接触史。结果表明，职业性接触百草枯并没有导致显著差异。以本研究选择的指标衡量，长期以所用浓度喷洒百草枯未对健康产生可量化的有害影响。
