Narayana A S, Loening S A, Culp D A
Br J Urol. 1981 Apr;53(2):152-3. doi: 10.1111/j.1464-410x.1981.tb03157.x.
Twenty-five patients with metastatic carcinoma of the prostate were treated with Flutamide, a non-steroidal anti-androgen. All patients showed progression; the longest response was 120 weeks. The side effects were nausea, vomiting, breast tenderness and gynaecomastia.
25例前列腺转移性癌患者接受了非甾体类抗雄激素药物氟他胺治疗。所有患者均出现病情进展;最长缓解期为120周。副作用包括恶心、呕吐、乳房压痛和男子女性型乳房。