Kanemitsu F, Kawanishi I, Mizushima J
Clin Chim Acta. 1981 May;112(3):275-83. doi: 10.1016/0009-8981(81)90450-2.
Three electrophoretically atypical creatine kinase (CK) bands were found simultaneously in the serum of a patient with terminal carcinoma of the colon. The atypical CKs were found at the cathodal side of CK-MB (CK-X1), at a sample application point (CK-X2), and at the anodal side of CK-MM (CK-X3) on agar plates. Our data seemed to suggest that CK-X1 was predominantly a CK-IgA/beta-lipoprotein complex, CK-X3 was a CK-IgG complex, and CK-X2 was macromolecular, different from both CK-X1 and CK-X3. The light chains of IgA and IgG were both of the lambda type. All native isoenzymes comprising these atypical CKs were identified as MM type. There was no change of the electrophoretic pattern of serum CK isoenzymes throughout the course of the study.
在一名晚期结肠癌患者的血清中同时发现了三条电泳非典型肌酸激酶（CK）带。在琼脂平板上，非典型CK分别位于CK-MB的阴极侧（CK-X1）、加样点（CK-X2）以及CK-MM的阳极侧（CK-X3）。我们的数据似乎表明，CK-X1主要是CK-IgA/β-脂蛋白复合物，CK-X3是CK-IgG复合物，而CK-X2是大分子物质，与CK-X1和CK-X3均不同。IgA和IgG的轻链均为λ型。构成这些非典型CK的所有天然同工酶均被鉴定为MM型。在整个研究过程中，血清CK同工酶的电泳图谱没有变化。
