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高渗性糖尿病昏迷中的肌红蛋白尿性肾衰竭(作者译)

[Myoglobinuric renal failure in hyperosmolar diabetic coma (author's transl)].

作者信息

Rumpf K W, Kaiser H, Gröne H J, Trapp V E, Meinck H M, Goebel H H, Kunze E, Kreuzer H, Scheler F

出版信息

Dtsch Med Wochenschr. 1981 May 29;106(22):708-11. doi: 10.1055/s-2008-1070386.

DOI:10.1055/s-2008-1070386
PMID:7238313
Abstract

Acute rhabdomyolysis with myoglobinuric renal failure occurred in a 66-year-old woman who was in hyperosmolar non-ketotic diabetic coma. No previous description of such a case has been found. The clinical picture was characterized by the typical findings of hyperosmolar coma, in addition to excessive serum creatine kinase and myoglobin levels and massive myoglobinuria with acute renal failure. The rhabdomyolysis became fully manifest only under insulin treatment, possibly the result of insulin-induced hypophosphataemia, which seems to be of importance in the causation of the rhabdomyolysis.

摘要

一名66岁处于高渗非酮症糖尿病昏迷状态的女性发生了急性横纹肌溶解症并伴有肌红蛋白尿性肾衰竭。此前未发现此类病例的描述。临床表现除了血清肌酸激酶和肌红蛋白水平过高以及伴有急性肾衰竭的大量肌红蛋白尿外,还具有高渗性昏迷的典型特征。横纹肌溶解症仅在胰岛素治疗下才完全显现,这可能是胰岛素诱导的低磷血症的结果,而低磷血症在横纹肌溶解症的病因中似乎很重要。

相似文献

1
[Myoglobinuric renal failure in hyperosmolar diabetic coma (author's transl)].高渗性糖尿病昏迷中的肌红蛋白尿性肾衰竭(作者译)
Dtsch Med Wochenschr. 1981 May 29;106(22):708-11. doi: 10.1055/s-2008-1070386.
2
[Nontraumatic rhabdomyolysis with reversible acute kidney failure following hyperosmolar diabetic coma in a child].[儿童高渗性糖尿病昏迷后出现可逆性急性肾衰竭的非创伤性横纹肌溶解症]
Monatsschr Kinderheilkd. 1984 Jan;132(1):51-4.
3
Hyperosmolar non-ketotic diabetic syndrome associated with rhabdomyolysis and acute renal failure: a case report and review of literature.高渗性非酮症糖尿病综合征合并横纹肌溶解症和急性肾衰竭:一例病例报告及文献复习
Diabetes Nutr Metab. 2003 Oct-Dec;16(5-6):317-22.
4
[Rhabdomyolysis as a cause of acute renal failure in hyperglycemic hyperosmolar nonketotic coma].[横纹肌溶解症作为高血糖高渗非酮症昏迷患者急性肾衰竭的病因]
Med Clin (Barc). 1989 Sep 16;93(7):278.
5
[Rhabdomyolysis related-acute renal failure in a patient with hyperosmolar nonketotic diabetic coma (HNKC): demonstration of myoglobin casts after normalization of renal function].[高渗性非酮症糖尿病昏迷(HNKC)患者的横纹肌溶解相关急性肾衰竭:肾功能恢复正常后肌红蛋白管型的表现]
Nihon Jinzo Gakkai Shi. 1996 Aug;38(8):388-92.
6
Rhabdomyolysis associated with hyperosmolar non--ketotic coma--a case report.横纹肌溶解症合并高渗性非酮症昏迷——病例报告
Zhonghua Yi Xue Za Zhi (Taipei). 1988 Apr;41(4):309-10.
7
[Rhabdomyolysis and non-ketotic hyperglycemic hyperosmolar coma].[横纹肌溶解症与非酮症高血糖高渗性昏迷]
Med Clin (Barc). 1986 May 31;87(1):41-2.
8
Fatal rhabdomyolysis associated with hyperosmolar diabetic decompensation.与高渗性糖尿病失代偿相关的致死性横纹肌溶解症。
Diabetes Res. 1988 Jun;8(2):97-9.
9
Hyperosmolal state associated with rhabdomyolysis.与横纹肌溶解相关的高渗状态。
Nephron. 1987;47(3):202-4. doi: 10.1159/000184492.
10
[Central core bodies and rhabdomyolysis in a case of hyperosmolar diabetic coma].
Rev Clin Esp. 1987 Feb;180(2):118-9.

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Biomolecules. 2018 Feb 8;8(1):9. doi: 10.3390/biom8010009.
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(R)-α-Lipoic acid inhibits fructose-induced myoglobin fructation and the formation of advanced glycation end products (AGEs) in vitro.(R)-α-硫辛酸在体外可抑制果糖诱导的肌红蛋白糖基化以及晚期糖基化终末产物(AGEs)的形成。
BMC Complement Altern Med. 2018 Jan 15;18(1):13. doi: 10.1186/s12906-017-2076-6.
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Non-enzymatic glycation induces structural modifications of myoglobin.
非酶糖基化诱导肌红蛋白结构修饰。
Mol Cell Biochem. 2010 May;338(1-2):105-14. doi: 10.1007/s11010-009-0343-7. Epub 2009 Nov 29.
4
Effect of non-enzymatic glycation on esterase activities of hemoglobin and myoglobin.非酶糖基化对血红蛋白和肌红蛋白酯酶活性的影响。
Mol Cell Biochem. 2007 Jul;301(1-2):251-7. doi: 10.1007/s11010-007-9418-5. Epub 2007 Feb 14.