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氨茶碱对人体作用后脂解作用增强，血浆肝素脂蛋白脂肪酶活性及α1脂蛋白水平降低。

Increase in lipolysis and decrease in plasma-heparin lipoprotein lipase activity and alpha 1 lipoprotein level after aminophylline in man.

作者信息

Zanaboni L, Bonfiglioli D, Sommariva D, D'Adda D, Fasoli A

出版信息

Eur J Clin Pharmacol. 1981;19(5):349-51. doi: 10.1007/BF00544585.

DOI:10.1007/BF00544585
PMID:7238563
Abstract

Intravenous aminophylline 0.48 g produced a sharp increase in plasma free fatty acids. After three days of treatment with aminophylline 0.96 g/day i.v., plasma post-heparin lipoprotein lipase was significantly reduced, and post-heparin hepatic triglyceridase remained unchanged. alpha 1 lipoprotein was reduced by treatment, in parallel with lipoprotein lipase, while other lipoprotein fractions, serum cholesterol and triglycerides were unaffected.

摘要

静脉注射0.48克氨茶碱可使血浆游离脂肪酸急剧增加。每天静脉注射0.96克氨茶碱治疗三天后，肝素后血浆脂蛋白脂肪酶显著降低，而肝素后肝甘油三酯酶保持不变。α1脂蛋白随着脂蛋白脂肪酶的降低而减少，而其他脂蛋白组分、血清胆固醇和甘油三酯未受影响。

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本文引用的文献

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A new assay for cholesterol and cholesterol esters in serum which is not affected by bilirubin.一种不受胆红素影响的血清胆固醇及胆固醇酯新检测法。
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Adenosine 3',5'-phosphate in biological materials. I. Purification and properties of cyclic 3',5'-nucleotide phosphodiesterase and use of this enzyme to characterize adenosine 3',5'-phosphate in human urine.生物材料中的3',5'-磷酸腺苷。I. 环3',5'-核苷酸磷酸二酯酶的纯化及性质，以及用该酶鉴定人尿中的3',5'-磷酸腺苷
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Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia.对正常受试者和高脂蛋白血症患者肝素化后血浆中两种脂肪酶活性的选择性测定。
J Clin Invest. 1974 Nov;54(5):1107-24. doi: 10.1172/JCI107855.
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Clearing-factor lipase in adipose tissue. A possible role of adenosine 3',5'-(cyclic)-monophosphate in the regulation of its activity.脂肪组织中的清除因子脂肪酶。3',5'-环磷酸腺苷在调节其活性中的可能作用。
Biochem J. 1968 Oct;109(5):841-9. doi: 10.1042/bj1090841.